Here is some comments on it: "At first I did have some nausea and flu like symptoms so my dr divided my dose over two nights. After about a month my body adjusted so I now take it at night around 9 PM and make sure I have something to eat like a banana or yogurt. I rarely suffer from any side effects. Once in a while I'll wake up with a little nausea but it is not a problem."
see also : https://www.arthritis.org/living-with-arthritis/treatments/medication/side-effects/understanding-medication-risks.php?utm_source=enewsletter&utm_medium=at&utm_campaign=183